With this query, the user specifies a protein kinase and a target phosphoprotein of interest to identify direct and indirect connections with possible intervening kinases between these proteins. The results are presented in a graphic chart. Apply the filters below to customize the output map.
Enter the first few characters for the name or UniProt ID of the protein kinase and then select the desired search term from the provided drop down list (required).
Enter the first few characters for the name or UniProt ID of the phosphoprotein substrate and then select the desired search term from the provided drop down list.
Use the pull-down menu below to specify the phosphosite in the queried substrate protein to identify the modifying kinases that target the phosphosite.
Boxes that are marked are activated to display substrates of this type. Click on checkboxes to change display specification.
Click on the buttons below to produce customized kinase-substrate interaction map or to reset the parameters.